Dentin Sialophosphoprotein Is Processed by MMP-2 and MMP-20 in Vitro and in Vivo
نویسندگان
چکیده
منابع مشابه
Dentin sialophosphoprotein is processed by MMP-2 and MMP-20 in vitro and in vivo.
Dentin sialophosphoprotein (DSPP) is a major secretory product of odontoblasts and is critical for proper tooth dentin formation. During dentinogenesis, DSPP is proteolytically cleaved into smaller subunits. These cleavages are proposed activation steps, and failure to make these cleavages is a potential cause of developmental tooth defects. We tested the hypothesis that dentin-resident matrix ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2006
ISSN: 0021-9258
DOI: 10.1074/jbc.m607767200